No appointments needed:
Montelena
Mondavi
Duckhorn
Nickel & Nickel
Berringer
Rombauer
Copolla
These are the "big" ones.
I suggest you drive south on 29 from St. Helena down to Yountville, cut across to the Silverado Trail and head north to Calistoga, and then south down 29 back to St. Helena. You will only have a few thousand wineries to choose from.
Here's a pretty good interactive map for the area.
Click on "Napa Valley Map" on this page.